I once visited a recently retired reverend whose wife had just left him and who was terminally ill with heart disease.  We talked about Paul's thorn in his side, and how this reverend was unable to handle the huge thorn in his side.  We consider the way that God created us: imperfectly, with imperfect lives.  We see that humility is the product of suffering, and that it has a number of major benefits, ones that greatly outweigh the benefit of having our thorn removed.