This episode discusses four MMWR reports. First, 2024-2025 COVID-19 vaccination provides additional protection against COVID-19-associated emergency department/urgent care encounters and hospitalizations. Second, this season's flu vaccines protect against flu-related medical visits and hospitalizations. Third, a new CDC report finds that 13% of children who have died from seasonal flu this season had influenza-associated encephalopathy or encephalitis, a potentially severe neurologic complication. Last, as HPV vaccination has increased, a steep decline in cervical precancers has occurred.