This week's episode covers five MMWR COVID-19 reports. The first describes that severe reactions following Pfizer-BioNTech COVID-19 vaccination appear to be very rare. Another report describes how U.S. counties with large colleges and universities saw a substantial increase in cases after starting in-person classes this fall. A third report shows how an increase in COVID-19 cases at an Arkansas university was linked to Greek Life activities. The last two reports provide data supporting options for health department to shorten quarantine periods.