This episode discusses four MMWR reports. The first report highlights the effectiveness of a COVID-19 additional primary or booster dose among nursing home residents. The second report examines modifiable risk factors for Alzheimer's disease and related dementias among adults aged 45 years and older. The third report highlights changes in firearm homicide and suicide rates in the United States from 2019 to 2020. And the last report looks at factors associated with HIV prevention and health care use among transgender women.