This episode discusses four MMWR reports. First, simulation models show that increasing mpox vaccination coverage among men who have sex with men can help reduce the risk for and size of future mpox outbreaks. Second, mpox prevention efforts should use equity-based strategies to reach gay, bisexual, and other men who have sex with men in urban areas. Third, updated COVID-19 vaccines help protect adults against COVID-19-associated hospitalization and critical illness. Finally, 2020 data show 6 in 10 violent deaths were suicides and 3 in 10 were homicides.