This episode discusses six MMWR reports. The first report examines wastewater testing and detection of poliovirus in New York. The second report describes severe monkeypox in hospitalized patients in the United States. The third report looks at flu-related hospitalizations and vaccination coverage by race and ethnicity in the United States. The fourth report looks at the timing and severity of Chile's most recent flu season and the effectiveness of the flu vaccine against hospitalization with influenza A(H3N2) viruses. The last two reports examine disparities in the outpatient treatment of COVID-19 in the United States.