This newsletter discusses the challenges of implementing generative AI in enterprises, highlighting the gap between initial enthusiasm and actual execution. A case study shows a successful implementation achieving a $15 million ROI, emphasizing the importance of persistence, starting small, and building a strong foundation. The newsletter recommends essential workstreams for AI councils, including strategic direction, ethical governance, and cross-functional collaboration. McKinsey research is cited, showing that only a small percentage of organizations see significant value from generative AI, underscoring the need for practical, phased approaches. The author shares his experiences advising clients in the healthcare and life sciences industries, but the lessons apply broadly across sectors.