First, cannabis-involved emergency department visits among children, teens, and young adults increased during the COVID-19 pandemic. Second, ongoing testing at a large school district in Missouri found respiratory viruses common among students and staff. Third, a new report describes recommendations for respiratory syncytial virus vaccination in adults 60 years and older, using shared clinical decision-making. Finally, cases of soft tick relapsing fever, a rare but serious tickborne disease, continue to occur in the western U.S.