There’s no paucity of studies for biologic therapies used to treat psoriatic disease, but the number of head-to-head trials comparing these agents is limited. Enter network meta-analysis, a statistical methodology that has emerged over the past few years to compare medication. Philip Mease, MD, a clinical professor at the University of Washington School of Medicine and director of rheumatology research at the Swedish Medical Center in Seattle, and Dr. Wolf-Henning Boehncke, chair of the division of dermatology and venereology at Geneva University Hospitals, Switzerland, and full professor at the Department of Pathology and Immunology at Geneva University, discuss the use of network meta-analyses and potential pitfalls in choosing biologic therapies for patients with psoriasis and psoriatic arthritis in this episode of Practical Dermatology: The Podcast.