What if diagnosing skin lesions didn’t require a scalpel — or even a biopsy at all? 

In this episode of First in Human, I sit down with Gabriel Sanchez, MIT-trained engineer, Stanford PhD, and founder and CEO of Enspectra Health. Early in his engineering career at Stanford, Gabriel began to see the limits of powerful imaging technologies that never made it beyond the lab. Instead of letting that work remain siloed, he set out to bring it into real clinical care. 

Gabriel tells the story of shrinking a room-sized microscope into a deployable medical device, and why he believes skin pathology is overdue for the same non-invasive transformation that reshaped radiology decades ago. We talk about the 150-year-old biopsy workflow that still defines dermatology, the massive bottlenecks it creates, and why so many attempts to change it have fallen short. 

Along the way, Gabriel shares what it really takes to introduce a brand-new imaging modality to the FDA, why studying past failures matters more than chasing hype, and how timing, patience, and persistence shape long innovation arcs. 

If you’ve ever wondered how scientific insight becomes real-world impact — or how medicine’s most entrenched habits actually change — this conversation offers a rare look inside the journey. 


Subscribe to First in Human: - Apple Podcasts: https://podcasts.apple.com/us/podcast/first-in-human/id1842644737 - Spotify: https://open.spotify.com/show/3C1xG5SxPei8m2lI63WSkd 
Check out Enspectra Health's Webpage: https://www.enspectrahealth.com/ 
Connect with Gabriel on LinkedIn: https://www.linkedin.com/in/gabriel-sanchez-a6719837/