Mismatch is a quick way to understand the underpinnings of almost all disease and malady. It’s also the key to solving for health problems. First, solve mismatch, then try other things. If you do not align yourself with your evolved biology, you’re setting yourself up for pain and disease. Humans, like all animals, have biological ‘edges’. Yes, we are adaptable, yes we are flexible but those adaptations are better applied to a hot desert or a cold tundra than to constant cell phone use or staying inside 23 of every 24 hours. This is a quick take on mismatch with some initial ideas on how to do a ‘mismatch check’ before you try more complicated solutions.