Powerbuilding is a training methodology that combines powerlifting and bodybuilding to increase both strength and muscle size. This newsletter offers evidence-based guidelines for creating an effective powerbuilding routine. Key considerations include training volume, repetition ranges, rate of perceived exertion (RPE), frequency, exercise order, range of motion, exercise selection and rest times. For strength, the recommendations suggest lower volume, heavier loads, lower RPE, and longer rest times, while hypertrophy benefits from higher volume, moderate reps, higher RPE, and shorter rest. The guidelines should be tailored to individual priorities, allowing for adjustments based on whether strength or hypertrophy is the primary goal. These guidelines promote the idea that optimal powerbuilding routines blend the two disciplines to achieve balanced gains.