Malcolm Gladwell joins host Dr. Eric Lander for a conversation about science, society, and how the decisions we make today will impact generations to come. At a moment when science is becoming more important than ever for meeting the challenges ahead, can we solve the growing tensions between society and science? 
 For links to materials referenced in the episode, suggestions for further learning, and guest bios, visit bravenewplanet.org.    Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

What’s at Stake

Utopia or dystopia? It’s up to us.In the 21st century, powerful technologies have been appearing at a breathtaking pace—related to the internet, artificial intelligence, genetic engineering, and more. They have amazing potential upsides, but we can’t ignore the serious risks that come with them.Brave New Planet is a podcast that delves deep into the most exciting and challenging scientific frontiers, helping us understand them and grapple with their implications. Dr. Eric Lander, president and founding director of the Broad Institute of MIT and Harvard, is a geneticist, molecular biologist, and mathematician who was a leader of the Human Genome Project and for eight years served as a science advisor to the White House for President Obama. He’s also the host of Brave New Planet, and he’s talked to leading researchers, journalists, doctors, policy makers, activists, and legal experts to illuminate how this generation’s choices will shape the future as never before.Brave New Planet is a partnership between the Broad Institute, Pushkin Industries, and The Boston Globe's Opinion team.

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The Happiness Lab’s Dr. Laurie Santos brings together other Pushkin hosts to mark the International Day of Happiness. Revisionist History’s Malcolm Gladwell talks about the benefits of the misery of running in a Canadian winter. Dr. Maya Shankar from A Slight Change of Plans talks about quieting her mental chatter. And Cautionary Tales host Tim Harford surprises everyone with the happiness lessons to be learned from a colonoscopy.
Hear more of The Happiness Lab HERE. See omnystudio.com/listener for privacy information.

Pushkin Hosts Celebrate World Happiness Day

While Andrea Rubin lay unconscious and severely burned after a car fire, her father told doctors to do everything they could to keep her alive. She would need many surgeries. Her quality of life wouldn’t be the same. Her friends were outraged. They told doctors that Andrea would not want to live that way. While Andrea was being kept alive on a ventilator, her loved ones fought about what would be best for her. In this episode, we explore how medical decisions are made for patients who are incapable of deciding for themselves. Enjoy this episode from playing god?

Show notes:
In addition to Andrea Rubin, this episode features interviews with:
Jeffrey Kahn, Andreas C. Dracopolous Director of the Johns Hopkins Berman Institute of Bioethics
Monica Gerrek, Co-director of the Center for Biomedical Ethics at MetroHealth System (where Andrea was treated)
You can learn more about Andrea’s case here. 
A similar case to Andrea’s happened in the 1970s. A man named Dax Cowart repeatedly asked doctors to let him die after suffering severe burns. But the doctors continued to treat him against his wishes. Here’s an interview with Mr. Cowart ten years after his accident, where he talks about his experience with the Washington Post. Dr. Gerrek wrote a paper comparing the two cases, and showing how medical decision making for severe burn patients has evolved over the past 50 years. 
For further reading about medical decision making and patient autonomy, visit the Berman Institute’s episode guide. 
The Greenwall Foundation. Making bioethics integral to decisions in healthcare, policy and research. Learn more at greenwall.org.  See omnystudio.com/listener for privacy information.

Introducing: playing god?

Open-source innovation is the future of AI. In this episode of Smart Talks with IBM, Malcolm Gladwell and Tim Harford discuss the open-source AI community with Jeff Boudier, head of product and growth at Hugging Face. They chat about the history and future of open-source AI, its critical importance to AI progress, the IBM watsonx partnership with Hugging Face, and how businesses can leverage open-source AI for their specific needs.
Visit us at: https://www.ibm.com/smarttalks/
Learn more about the Hugging Face partnership: https://newsroom.ibm.com/2023-08-24-IBM-to-Participate-in-235M-Series-D-Funding-Round-of-Hugging-Face 
Learn more about the Google DeepMind paper referenced in this episode:  https://proceedings.neurips.cc/paper_files/paper/2017/file/3f5ee243547dee91fbd053c1c4a845aa-Paper.pdf
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Hugging Face and watsonx: Why Open Source Is the Future of AI in Business

What is ‘structure-based’ vaccine design? Before scientists used these techniques to design vaccines against Covid, they were testing them in the lab to combat RSV. Keren Landman joins the show to talk about how this respiratory virus endangers the lives of babies and the elderly. Then, we hear about an early RSV vaccine trial that cast a shadow over modern research, and how scientists, including our guests Jason McLellan and Barney Graham, later figured out how to create and stabilize a viral antigen’s spike protein to fight RSV. See omnystudio.com/listener for privacy information.

RSV: The Quest for a New Vaccine

What can we learn from the centuries-long quest to eradicate smallpox, once the scourge of humanity? And how did it set the stage for all vaccines to come? First we meet Edward Jenner, a doctor in 18th century Britain who learned about the folk practice of “variolation” and found a safer way to inoculate people against smallpox. Then, Donald Hopkins of the Carter Center takes us back to the 1960s in Sierra Leone, where he discovered that successfully eradicating smallpox could be a feasible goal worldwide. Enjoy this episode from Incubation, another Pushkin podcast. See omnystudio.com/listener for privacy information.

What’s at Stake

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