So keep in mind that what you learn today

Might be slightly out of date

By the time you graduate

When safety signals start to show

Sometimes medications have to go

Darvocet, an opioid was widely prescribed for years

But fatal heart issues led to lots of tears

Post-marketing surveillance is key

We keep watching drugs even after they're released

Phase IV never really ends

Cause we're always tracking adverse events

Cylert was a stimulant for treating ADHD

But it was withdrawn because of severe hepatotoxicity

Vioxx nearly doubled the risk of heart attack or stroke

So it was pulled too cause that’s no joke

But not every risky drug goes away completely

Especially if it provides benefits uniquely

Sometimes a strong warning is given instead

So everyone’s informed about the risks ahead

A black box warning was added for Celebrex

Cause this COX-2 inhibitor increases the risk of GI events

As well as the risk of heart attacks and strokes

So the FDA decided they should warn folks

Post-marketing surveillance is key

We keep watching drugs even after they're released

Phase IV never really ends

Cause we're always tracking adverse events

New data and updates can easily accrue

So staying current is what you gotta do

Post-marketing surveillance is key

We keep watching drugs even after they're released

Phase IV never really ends

Cause we're always tracking adverse events

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