A 2026 BMJ systematic review confirms that weight regain is the rule after stopping pharmacological weight-management therapy. Across drug classes, most lost weight is regained within 24 months, with parallel loss of metabolic benefit. This reflects biological defence of adiposity, not patient failure.<a href="https://www.scvc.co.uk/metabolic-health/why-glp-1-withdrawal-trials-fail-and-why-cardiometabolic-care-must-look-different/">Blog</a>

A 2026 BMJ systematic review confirms that weight regain is the rule after stopping pharmacological weight-management therapy. Across drug classes, most lost weight is regained within 24 months, with parallel loss of metabolic benefit. This reflects biological defence of adiposity, not patient failure. Blog

A 2026 BMJ systematic review confirms that weight regain is the rule after stopping pharmacological weight-management therapy. Across drug classes, most lost weight is regained within 24 months, with parallel loss of metabolic benefit. This reflects biological defence of adiposity, not patient failure.<a href="https://www.scvc.co.uk/metabolic-health/why-glp-1-withdrawal-trials-fail-and-why-cardiometabolic-care-must-look-different/" rel="noopener noreferrer">Blog</a>&nbsp;

Why GLP-1 Withdrawal Trials Fail — and Why Cardiometabolic Care Must Look Different

The VAT Trap book, blog and digital media series reveals how visceral fat — the hidden metabolic organ — drives heart disease, hypertension, and diabetes. Drawing on 30 years of frontline cardiology and the latest in imaging, app-based tracking, and metabolic science, Dr Ed Leatham translates complex research into clear, actionable steps. Whether you want to avoid heart disease, stabilise your metabolism, or understand GLP-1 therapy, these four concise podcast seasons accompany a four book series that will help you see, track, and reverse the VAT trap. 

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The VAT Trap book, blog and digital media series reveals how visceral fat — the hidden metabolic organ — drives heart disease, hypertension, and diabetes. Drawing on 30 years of frontline cardiology and the latest in imaging, app-based tracking, and metabolic science, Dr Ed Leatham translates complex research into clear, actionable steps. Whether you want to avoid heart disease, stabilise your metabolism, or understand GLP-1 therapy, these four concise podcast seasons accompany a four book series that will help you see, track, and reverse the VAT trap. To join the mailing list click on the link below and add your email https://link.scvc.co.uk/vat-trap-join-newsletter

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Why GLP-1 Withdrawal Trials Fail — and Why Cardiometabolic Care Must Look Different

Why GLP-1 Withdrawal Trials Fail — and Why Cardiometabolic Care Must Look Different