In this episode, Dr. John Bartlett recaps the rise and fall of the Panton-Valentine leukocidin (PVL) exotoxin as a suspect in high mortality and devastating infections related to methicillin-resistant Staphylococcus aureus (MRSA). The story starts in France and goes global, with a stop in the locker room of the St. Louis Rams football team! Find out why PVL is still important today.