Join Juanita and Jackson as they discuss dating individuals with STD or STI is it something you could do? Whats the difference? STD stands for sexually transmitted disease, where as STI means sexually transmitted infection. Essentially, the difference is between a disease and an infection. Not all diseases begin with infections, but many do. Listen as these friends share their thoughts on the possibility of dating individuals with STD/STI's. Maybe you've thought about it or experienced it. Tune in lets share!