The era of AI agents managing their own digital identities is here. We explore AgentMail, a Y Combinator-backed startup that flips the script on AI email tools by giving machines their own programmable inboxes. Learn why email remains the universal protocol for AI communication, how it provides persistent memory and audit trails, and what this shift means for the future of autonomous work. From agent-to-agent negotiations to the challenge of AI spam, this episode dives into the plumbing of agentic infrastructure.