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There is an activated condition of mast cells in long COVID-19, with abnormal granulation and excessive inflammatory cytokine release. A study by Weinstock et al. indicates that patients with long COVID-19 suffer the same clinical syndrome as patients with mast cell activation syndrome (MCAS).
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166245/#:~:text=There%20is%20an%20activated%20condition,cell%20activation%20syndrome%20(MCAS).

Mast cell activation triggered by SARS-CoV-2 causes inflammation in brain microvascular endothelial cells and microglia
  https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2024.1358873/full  

Detoxing from the spike protein and the role of MCAS
Dr Tina Peers
 https://www.youtube.com/watch?v=hzl93aUtRR0

Mast Cell Activation Syndrome :
The Interplay Between Immunity and Neuroinflammation
 Dr. Tania Dempsey
https://www.youtube.com/watch?v=9w0VeJkACI8&t=18s

Hypoxia regulates human mast cell adhesion to fibronectin via the PI3K/AKT signaling pathway
  https://ww

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