From Concept to Medicine - A Comprehensive Drug Development Journey

104 – Advanced Drug Delivery Systems (S7E14)


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This episode explores next-generation drug delivery technologies, including nanocarriers, liposomes, and implantable devices. It delves into the science behind these innovations, highlighting their advantages over conventional methods and showcasing their real-world clinical applications. The discussion emphasizes how these advanced systems improve drug efficacy, reduce side effects, and enable targeted therapies, providing practical examples.

Beyond simply administering medication, advanced drug delivery systems aim to optimize drug distribution and efficacy within the body. The episode highlights the enhanced permeation and retention (EPR) effect of nanocarriers in targeting diseased tissues and the versatility of liposomes in improving drug solubility and protecting drugs from degradation. Furthermore, the discussion explores the benefits of implantable devices for delivering medication over extended periods, reducing the frequency of dosing and maintaining consistent drug levels. The episode also touches on the regulatory challenges and safety considerations associated with these advanced systems, emphasizing the need for rigorous testing and careful monitoring. Finally, the episode explores the broader applications of these technologies beyond cancer and inflammatory diseases, including their potential use in treating infectious diseases and neurological disorders.

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From Concept to Medicine - A Comprehensive Drug Development JourneyBy Jim Mitchell

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