The study explores how Notch2 signaling manages the structural organization of lymph nodes by directing the development of specialized fibroblastic reticular cells. Researchers identified a unique circuit where homeostatic mature dendritic cells provide continuous Jagged1 signals to maintain a specific population of Ccl19-high fibroblasts in the central T cell zone. This interaction creates distin...去小宇宙查看完整单集简介
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