This article from Cancer Cell investigates why some urothelial cancers develop resistance to the antibody-drug conjugate (ADC) Enfortumab vedotin (NECTIN4-ADC). Using single-cell RNA sequencing and spatial transcriptomics, researchers identified a specific tumor cell subpopulation that remains high in NECTIN4 expression but evades treatment through endocytic trafficking defects. The study reveals ...去小宇宙查看完整单集简介
前往小宇宙评论区与主播互动