Paper Talk

1096-Ketogenesis-Ferroptosis Axis in Leukemic Stem Cell


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This research identifies a self-contained ketogenic pathway that is essential for the survival of leukemic stem cells (LSCs) in acute myeloid leukemia. While ketone production is typically associated with the liver, these malignant cells utilize fatty acid oxidation to generate the ketone body BHB, which acts as a protective shield against cell death. This metabolic process works by epigenetically...去小宇宙查看完整单集简介
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Paper TalkBy 淼淼Elva