Wild & Well Collective

110. Histamine Overload: The Link Between Food, Stress, Hormones & Your Symptoms

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Histamine isn’t just about allergies; it plays a powerful role in our hormones, gut health, mood, and overall well-being. In this episode, Christa Elza and Sheree Beaumont unpack the often-overlooked impact of histamine intolerance, from anxiety and migraines to PMS, skin reactions, and digestive distress. Together, they explore how histamine interacts with estrogen, the genetic factors that influence its breakdown, and the roles of diet, stress, and gut health in tipping the “histamine bucket.” 

 

With practical strategies, supplement insights, and hormone-balancing tips, this conversation equips you with the knowledge to identify triggers, restore balance, and reclaim your energy and clarity.

 

[00:00 – 06:59] Histamine Basics & Everyday Triggers

  • Histamine is a signaling molecule, vital but harmful in excess
  • Common symptoms: headaches, bloating, hives, congestion, anxiety
  • Everyday triggers include stress, alcohol, allergens, mold, and toxins
  • Balance is key: too much or too little histamine causes problems

    • [07:00 – 11:59] Hormones, Ovulation & Estrogen’s Role

    • Estrogen stimulates mast cells to release histamine
    • Histamine feeds back and increases estrogen, creating a vicious cycle
    • Symptoms often worsen around ovulation or PMS (anxiety, migraines, hives)
    • Progesterone has a calming effect, but declines in perimenopause raise risk

      • [12:00 – 15:59] Food, Genetics & The Histamine Bucket

      • High-histamine foods: aged cheese, cured meats, red wine, fermented foods
      • Histamine liberators: citrus, strawberries, chocolate, shellfish, leftovers
      • Genetics (DAO & MTHFR variants) can impair histamine breakdown
      • Supplements like DAO enzyme, methylated B vitamins, NAC, and milk thistle support balance

        • [16:00 – 18:59] Gut Health & Lifestyle Factors

        • Gut permeability and bacterial imbalance heighten histamine load
        • Medications like NSAIDs, antibiotics, and antidepressants may suppress DAO
        • Healing strategies: glutamine, zinc carnosine, collagen, bifido-rich probiotics
        • Dairy sensitivity and stress often worsen histamine reactions

          • [19:00 – 22:00] Post-Menopause & Practical Action Steps

          • Lower estrogen post-menopause can reduce one trigger, but gut issues remain
          • Key steps: track symptoms, food journaling, and identify stress levels
          • Focus on gut repair, probiotics, supplements, and hormone testing if needed
          • Stress management is essential, mast cells release histamine under stress

            •  

            Key Quotes:

            “Histamine is kind of like an allergy molecule, it can impact digestion, hormones, mood, and even anxiety.” – Christa Elza

             

            “Empowered health is your superpower. Knowing your triggers puts the solution back in your hands.” – Sheree Beaumont




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            Wild & Well CollectiveBy Christa Elza & Sheree Hannah