Paper Talk

1107-TPPP/p25 Amyloid Seeding Activity for MSA


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This research identifies the tubulin polymerization promoting protein (TPPP/p25) as a highly specific biomarker for diagnosing multiple system atrophy (MSA). Researchers discovered that while the protein's native state is self-protected from aggregation, its core domain (CORE) is prone to forming toxic amyloid fibrils that distinguish MSA from related conditions like Parkinson’s disease. Using cry...去小宇宙查看完整单集简介
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Paper TalkBy 淼淼Elva