Paper Talk

1170-D&D-seq: Single-Cell DNA-Protein Interactions


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Researchers have developed D&D-seq, a novel single-cell technology designed to map DNA-protein interactions, even those that are weak or transient. By fusing a cytosine base editor to a nanobody, the method induces specific C-to-U mutations at sites where proteins like transcription factors are bound to the genome. This technique addresses the limitations of older methods that struggled with low-i...去小宇宙查看完整单集简介
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Paper TalkBy 淼淼Elva