This research introduces Mitotrek, a novel multi-omic method that utilizes mitochondrial DNA (mtDNA) mutations to trace the lineage of innate immune cells in human lung and ovarian cancers. By analyzing single-cell data from matched tumors, tissues, and blood, the researchers discovered that tumor-resident myeloid cells, such as macrophages and dendritic cells, originate from circulating monocytes...去小宇宙查看完整单集简介
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