This research examines how dopamine pathways connecting the ventral tegmental area (VTA) and the orbitofrontal cortex (OFC) regulate chronic pain and associated emotional disorders. Using a mouse model of trigeminal neuralgia, the authors identified a hypodopaminergic state that drives both physical sensitivity and depressive behaviors. The study reveals that two distinct dopamine receptors in the...去小宇宙查看完整单集简介
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