This paper introduces Genotyping in Fixed Transcriptomes (GIFT), a novel single-cell sequencing method that simultaneously measures gene expression and genetic mutations. The technology uses single-stranded DNA probes and a gapfilling reaction to identify hundreds of targeted mutations with over 99% accuracy. Unlike previous techniques, GIFT works effectively on formalin-fixed (FFPE) archival tiss...去小宇宙查看完整单集简介
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