Paper Talk

1230-Confined Neuronal Migration Induces DNA Damage


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A study reveals that developing neurons experience significant DNA double-stranded breaks as they migrate through narrow spaces in the brain. Unlike cancer cells, which often suffer DNA damage due to nuclear envelope rupture, these neurons maintain their membrane integrity while experiencing mechanical stress. Researchers discovered that this damage is primarily linked to topoisomerase-IIβ activit...去小宇宙查看完整单集简介
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Paper TalkBy 淼淼Elva