This manuscript examines the emergence of neuroendocrine differentiation (NED) during the early stages of prostate cancer progression. By utilizing spatial transcriptomics and single-cell RNA sequencing, researchers identified a distinct molecular subtype in hormone-sensitive tissues that predicts a poor clinical prognosis. The study established a six-gene biomarker panel—comprising FMN2, APLP1, S...去小宇宙查看完整单集简介
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