The paper details the creation of the eORFeome, a comprehensive functional genomics library containing nearly 4,000 pathogen effector proteins from various viruses, bacteria, and parasites. By utilizing high-throughput lentiviral screens, researchers systematically mapped how these effectors manipulate core human cellular processes, including immune signaling, apoptosis, and DNA damage responses. ...去小宇宙查看完整单集简介
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