First Principles of Medicine

#14A - Sepsis: more than just bugs and blood


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The First Principles of Sepsis that can get you through any placement: What is it? How do you recognise it? What do you do about it? Is a lumbar puncture a bedside investigation?

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Check out our new website ⁠1pm.wiki⁠ for the ⁠Notion document⁠, free Anki flashcards, and podcast episodes.

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Recorded 28 February 2023 Co-hosts: Joshua Naylor, Jason D'Silva, Jayanth Cheyyur feat. Nhien Huynh. Produced by JT Yeung⁠ & Adian Izwan.

If you have any ideas or feedback, comment on this Notion document, or shoot us an email at [email protected]

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We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce infographics for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.

You can check her out on instagram at @beckysnotes01 and get her books at ⁠https://linktr.ee/Beckysnotes⁠

=== Timestamps ===

(00:56) Defining sepsis

(02:24) Causes of sepsis 

(04:29) Risk factors

(06:12) BASIC 

(07:00) Pathophysiology of sepsis

(13:22) Disseminated Intravascular Coagulation

(15:03) Clinical features

(19:49) qSOFA

(21:19) Investigations

(25:36) Management

(28:56) Antibiotics according to ETG

(30:03) Complications 

(31:32) 3 Key Takeaways

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First Principles of MedicineBy 1PM