Prostate Cancer and BPH are very common conditions in the elderly males. They are very common conditions in the hospital setting, and medical students are bound to encounter it whilst on their rotations. We hope that this podcast will be able to set you up for success in your coming rotations or act as a nice revision for you ongoing studies.

Join us in reaching deep into the prostate and it's pathology - not just with your mind, but also a finger 🫢

#41 - Prostate Cancer & BPH

=== Other Links ===

1PM Website

Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes.

Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Recorded 2nd June, 2026. Hosts: Eric Ny, Sithum Fernando, Titus Leong, Truman Lo . Produced by Eric Ny.

If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠[email protected]⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

© First Principles of Medicine 2026

First Principles of Anaphylaxis:

Anaphylaxis is one of those conditions you never want to miss, but it can be stressful knowing exactly what to do when every second counts. In this episode, we break it all down from first principles.

We'll cover how to recognise anaphylaxis early, what's actually happening in the body, why adrenaline is the treatment of choice, and the key steps in management. As always, this isn't about memorising guidelines, it's about understanding the why behind your decisions, so you'll feel more confident in OSCEs, on the wards, and in clinical practice.

So grab your matcha, your laptop, or your favourite study snack (just maybe double check it isn't hiding any peanuts 🥜), and let's dive into anaphylaxis. From airway and breathing checks to adrenaline and beyond, because knowing what to do in those first few moments can make all the difference.

=== Other Links ===

Notion notes: https://app.notion.com/p/1pm/40-Anaphylaxis-3b9ef1d0b55f801dbfb1f285f3de9da9?source=copy_link

================

Recording date: 27/5/2026

Guests: Angela Goh, Julia Jolly and Jasmyne Le

Producer: Jasmyne Le

First Principles of Abnormal Uterine Bleeding (AUB)

In this episode, we're going to break it all down from first principles. We'll walk through how to take a focused history without getting lost in the menstrual timeline, what investigations actually matter (and which ones don't), and how management changes depending on what's causing the bleeding.

As always, this isn't about memorising endless lists. It's about understanding the why behind the questions you ask and the tests you order, so the next time you're on ward rounds or in an OSCE, you'll know exactly where to start.

So grab your coffee, your notebook, or your favourite study snack, and let's dive into abnormal uterine bleeding—because periods might be monthly, but OSCEs can ask about them any day of the year!

Disclaimer: This episode was recorded on 8 May 2026. At the time of recording, the condition now known as Polyendocrine Metabolic Ovarian Syndrome (PMOS) was referred to as Polycystic Ovary Syndrome (PCOS). Following the official nomenclature change announced on 12 May 2026, the term PMOS is now preferred. References to "PCOS" in this episode reflect the terminology that was in use at the time of recording.

Check out the online note here: ⁠https://1pm.notion.site/39-Abnormal-Uterine-Bleeding-37def1d0b55f803e8439dbd37275bf2c⁠

=== Other Links ===

1PM Website

Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes.

Instagram 

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Recorded 8 May 2026.

Hosts: Angela Goh, Julia Jolly, Jasmyne Le

Produced by Angela Goh.

If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠[email protected]⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

© First Principles of Medicine 2025

First Principles of Abnormal Uterine Bleeding (AUB)

Think it's "just PMS"? Think again! In Part I of our AUB series, we dive into what counts as normal menstrual bleeding, when bleeding becomes abnormal, and the common causes behind it. Join us as we unpack the basics of Abnormal Uterine Bleeding and turn a confusing topic into something clear, practical, and surprisingly fascinating.

Disclaimer: This episode was recorded on 1 May 2026. At the time of recording, the condition now known as Polyendocrine Metabolic Ovarian Syndrome (PMOS) was referred to as Polycystic Ovary Syndrome (PCOS). Following the official nomenclature change announced on 12 May 2026, the term PMOS is now preferred. References to "PCOS" in this episode reflect the terminology that was in use at the time of recording.

Check out the online note here: https://1pm.notion.site/39-Abnormal-Uterine-Bleeding-37def1d0b55f803e8439dbd37275bf2c

=== Other Links ===

1PM Website

Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes.

Instagram 

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Recorded 1 May 2026.

Hosts: Angela Goh, Andreana Goh, Julia Jolly.

Produced by Angela Goh.

If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠[email protected]⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

© First Principles of Medicine 2025

The First Principles of Seizures (Summary): Join us for the summary version of our seizures episode.

⁠1PM Notion: Seizures⁠

=== Other Links ===

1PM Website

Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes.

Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Recorded 27th of July, 2025. Hosts: Benjamin Earner, Saud Rana, Jasper Jackson. Produced by Benjamin Earner.

If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠[email protected]⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

© First Principles of Medicine 2025

The First Principles of Seizure: Join us as we explore the electrifying world of seizures and epilepsy. We hope this episode will provide you with a clearer framework to describe, investigate, diagnose, and manage seizures from a patient’s first seizure to the emergency of status epilepticus.

1PM Notion: Seizures

=== Other Links ===

1PM Website

Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes.

Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Recorded 27th of July, 2025. Hosts: Benjamin Earner, Saud Rana, Jasper Jackson. Produced by Benjamin Earner.

If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠[email protected]⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

© First Principles of Medicine 2025

The First Principles of The Limping Child

Summary version of "The Limping Child," best used as brief revision of key concepts explored in the original episode.

=== Other Links ===

Check out our notion document on this topic:

https://www.notion.so/1pm/37-The-Limping-Child-261ef1d0b55f80bf84e1eb1b3a86b736

Check out our website 1pm .wiki for the Notion document, free Anki flashcards, and podcast episodes.

Instagram: https://www.instagram.com/firstprinciplesofmedicine/

Recorded May 2025. Hosts: Abdulla Ellagta, Norman Luyt, Danial Khong

Produced by Abdulla Ellagta

If you have any ideas or feedback, comment on the Notion document, or shoot us an email at [email protected]

© First Principles of Medicine 2025

The First Principles of The Limping Child

In this episode we seek to break down a common paediatric presentation into the essentials, primarily covering a systematic approach to differentiating the causative pathologies. Join us as we limp towards a diagnosis.

=== Other Links ===

Check out our notion document on this topic:

https://www.notion.so/1pm/37-The-Limping-Child-261ef1d0b55f80bf84e1eb1b3a86b736

Check out our website 1pm .wiki for the Notion document, free Anki flashcards, and podcast episodes.

Instagram: https://www.instagram.com/firstprinciplesofmedicine/

Recorded May 2025. Hosts: Abdulla Ellagta, Norman Luyt, Danial Khong

Produced by Abdulla Ellagta

If you have any ideas or feedback, comment on this Notion document, or shoot us an email at [email protected]

© First Principles of Medicine 2025

The First Principles of osteoporosis: Join us for the summary version of this episode for a quick run down on the presentation, diagnosis and management of osteoporosis.

=== Other Links ===

1PM Website

https://1pm.notion.site/36-Osteoporosis-24cef1d0b55f8063ba30cc625d2c8122?source=copy_link

Check out our new website 1pm .wiki for the Notion document, free Anki flashcards, and

podcast episodes.

Instagram: https://www.instagram.com/firstprinciplesofmedicine/

Recorded May 2025. Hosts: Norman Luyt, Elliott Willis, Danial Khong

Produced by Norman Luyt.

If you have any ideas or feedback, comment on this Notion document, or shoot us an email

at [email protected]

© First Principles of Medicine 2025

The First Principles of osteoporosis: Join us as we discuss the pathophysiology, diagnosis and management of osteoporosis, a common condition which you will encounter throughout your medical career.

=== Other Links ===

1PM Website

https://1pm.notion.site/36-Osteoporosis-24cef1d0b55f8063ba30cc625d2c8122?source=copy_link

Check out our new website 1pm .wiki for the Notion document, free Anki flashcards, and

podcast episodes.

Instagram: https://www.instagram.com/firstprinciplesofmedicine/

Recorded May 2025. Hosts: Norman Luyt, Elliott Willis, Danial Khong

Produced by Norman Luyt.

If you have any ideas or feedback, comment on this Notion document, or shoot us an email

at [email protected]

© First Principles of Medicine 2025