First Principles of Medicine

By 1PM

🌐 1PM.WIKI 🌐

🔍 🎲 Welcome to 1PM, in this series we will be breaking down complex medical topics into their First Principles.

😟 When the stress is on, and you’ve just been asked a tough question... more

Download on the App Store

Download on the App Store

Get it on Google Play

FAQs about First Principles of Medicine:

How many episodes does First Principles of Medicine have?

The podcast currently has 73 episodes available.

First Principles of Medicine episodes:

June 10, 2023 #17A - Antipsychotics: the First Principles of pathways
The First Principles of Antipsychotics that can more than get you through your psychiatry rotation: is it all about the dopamine?

=== Other Links ===
Check out our new website ⁠⁠⁠1pm.wiki⁠⁠⁠ for the ⁠⁠⁠Notion document⁠⁠⁠, free Anki flashcards, and podcast episodes.
Check out our Instagram: ⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠
Recorded 7 March 2023 Co-hosts: Broska Zeynel & Jason D'Silva feat. Renae Long & Alexander Lawrie. Produced by Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠[email protected]⁠⁠⁠
***
We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce infographics for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.
You can check her out on Instagram at @beckysnotes01 and get her books at ⁠⁠⁠https://linktr.ee/Beckysnotes⁠⁠⁠

=== Timestamps ===
(01:33) The First Principles of pathways
(02:59) Dopaminergic pathways
(03:28) Mesolimbic - positive symptoms
(04:13) Mesocortical - negative symptoms
(07:17) Nigrostriatal - motor symptoms
(08:15) Tuberoinfundibular - prolactin
(09:06) Pathway summary
(10:53) Other receptors
(13:47) Antipsychotics (finally)
(14:19) Typical antipsychotics
(17:43) Negative symptoms mnemonic
(19:36) Neuroleptic malignant syndrome
(22:28) Atypical antipsychotics
(24:23) Metabolic side effects
(25:07) Summary

...more
30min
May 07, 2023 #16 - RUQ Pain: if you in-cyst
The First Principles of Right Upper Quadrant Pain that can get you through your general surgical rotation: Dr Sherman Kwan takes us through what we NEED to know about gallstones, the biliary tree, and everything in between.

=== Other Links ===
Check out our new website ⁠⁠⁠1pm.wiki⁠⁠⁠ for the ⁠⁠⁠Notion document⁠⁠⁠, free Anki flashcards, and podcast episodes.
Check out our Instagram: ⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠
Recorded 26 July 2022 Co-hosts: Jason D'Silva, Daniel Bontempo, ⁠⁠⁠⁠⁠⁠⁠JT Yeung⁠⁠⁠⁠ & Adian Izwan feat. Dr Sherman Kwan. Produced by Jason D'Silva & Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠[email protected]⁠⁠⁠
***
We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce an infographic for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.
You can check her out on instagram at @beckysnotes01 and get her books at ⁠⁠⁠https://linktr.ee/Beckysnotes⁠⁠⁠

=== Timestamps ===
(02:37) What is the Gallbladder?
(06:07) Admirand's Triangle
(07:52) Colicky Pain
(09:42) The Biliary Tree
(11:16) Bugs in the Tubes
(11:43) The Case
(12:29) The A to E
(15:30) The History
(20:14) Red Flags
(22:33) Examination Findings
(28:01) Murphy's Sign
(29:42) Urinalysis
(31:18) Investigations - Bloods
(34:51) Investigations - Imaging
(35:50) Management

...more
43min
April 23, 2023 #15B - Febrile Neutropenia...in 5 minutes!
The First Principles of Febrile Neutropenia that can get you through an oncological emergency: First Principles summary version.
=== Other Links ===
Check out our new website ⁠⁠⁠1pm.wiki⁠⁠⁠ for the ⁠⁠⁠Notion document⁠⁠⁠, free Anki flashcards, and podcast episodes.
Check out our Instagram: ⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠
Recorded 22 March 2023 Co-hosts: ⁠⁠⁠⁠⁠⁠⁠JT Yeung⁠⁠⁠⁠ & Adian Izwan feat. Michael Offerman & Lucy Variakojis. Produced by Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠[email protected]⁠⁠
***
We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce infographics for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.
You can check her out on instagram at @beckysnotes01 and get her books at ⁠⁠⁠https://linktr.ee/Beckysnotes⁠
...more
3min
April 23, 2023 #15A - Febrile Neutropenia: feverish importance
The First Principles of Febrile Neutropenia that can get you through an oncological emergency: What are neutrophils, what do they do, and how many do we need?
=== Other Links ===
Check out our new website ⁠⁠1pm.wiki⁠⁠ for the ⁠⁠Notion document⁠⁠, free Anki flashcards, and podcast episodes.
Check out our Instagram: ⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠
Recorded 22 March 2023 Co-hosts: ⁠⁠⁠⁠JT Yeung⁠⁠⁠ & Adian Izwan feat. Michael Offerman & Lucy Variakojis. Produced by Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠[email protected]⁠⁠
***
We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce an infographic for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.
You can check her out on instagram at @beckysnotes01 and get her books at ⁠⁠https://linktr.ee/Beckysnotes⁠⁠
=== Timestamps ===
(01:31) Normal body temperature
(02:02) Neutrophils & bone marrow
(06:06) Normal neutrophil ranges
(08:35) Decreased making vs increased breaking
(11:29) What is febrile neutropenia
(13:31) MASC risk index
(14:47) Clinical features
(16:21) Investigations
(20:14) Michael's oncological emergency
(22:41) Management
(29:55) 3 key takeaways
...more
32min
April 04, 2023 #14B - Sepsis: OSCE-style summary
The First Principles of Sepsis that can get you through any placement: First Principles summary version.
=== Other Links ===
Check out our new website ⁠1pm.wiki⁠ for the ⁠Notion document⁠, free Anki flashcards, and podcast episodes.
Check out our Instagram: ⁠https://www.instagram.com/firstprinciplesofmedicine/⁠
Recorded 28 February 2023 Co-hosts: ⁠⁠⁠Joshua Naylor, Jason D'Silva, Jayanth Cheyyur feat. Nhien Huynh. Produced by ⁠JT Yeung⁠⁠ & Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠[email protected]⁠
***
We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce infographics for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.
You can check her out on instagram at @beckysnotes01 and get her books at ⁠⁠https://linktr.ee/Beckysnotes⁠
...more
7min
April 04, 2023 #14A - Sepsis: more than just bugs and blood
The First Principles of Sepsis that can get you through any placement: What is it? How do you recognise it? What do you do about it? Is a lumbar puncture a bedside investigation?
=== Other Links ===
Check out our new website ⁠1pm.wiki⁠ for the ⁠Notion document⁠, free Anki flashcards, and podcast episodes.
Check out our Instagram: ⁠https://www.instagram.com/firstprinciplesofmedicine/⁠
Recorded 28 February 2023 Co-hosts: ⁠Joshua Naylor, Jason D'Silva, Jayanth Cheyyur feat. Nhien Huynh. Produced by JT Yeung⁠ & Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠[email protected]⁠
***
We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce infographics for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.
You can check her out on instagram at @beckysnotes01 and get her books at ⁠https://linktr.ee/Beckysnotes⁠
=== Timestamps ===
(00:56) Defining sepsis
(02:24) Causes of sepsis
(04:29) Risk factors
(06:12) BASIC
(07:00) Pathophysiology of sepsis
(13:22) Disseminated Intravascular Coagulation
(15:03) Clinical features
(19:49) qSOFA
(21:19) Investigations
(25:36) Management
(28:56) Antibiotics according to ETG
(30:03) Complications
(31:32) 3 Key Takeaways
...more
34min
March 17, 2023 #13B - Acute Coronary Syndromes: OSCE-style summary
The First Principles of Acute Coronary Syndromes that can get you through your Internal Medicine placements: First Principles summary version.
=== Other Links ===
Check out our new website 1pm.wiki for the Notion document, free Anki flashcards, and podcast episodes.
Check out our Instagram: https://www.instagram.com/firstprinciplesofmedicine/
Recorded 6 September 2022 Co-hosts: JT Yeung, Jason D’Silva, Adian Izwan & Daniel Bontempo feat. Jayanth Cheyyur. Produced by Evangelyn Sim, JT Yeung & Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at [email protected]
***
We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce an infographic on ACS for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.
You can check her out on instagram at @beckysnotes01 and get her books at ⁠https://linktr.ee/Beckysnotes⁠
...more
4min
March 16, 2023 #13A - Acute Coronary Syndromes: non-modifiable pronunciations
The First Principles of Acute Coronary Syndromes that can get you through your Internal Medicine placements: What are they? What are the ECG changes? How do you ask about the risk factors?
=== Other Links ===
Check out our new website 1pm.wiki for the Notion document, free Anki flashcards, and podcast episodes.
Check out our Instagram: https://www.instagram.com/firstprinciplesofmedicine/
Recorded 6 September 2022 Co-hosts: JT Yeung, Jason D’Silva, Adian Izwan & Daniel Bontempo feat. Jayanth Cheyyur. Produced by Evangelyn Sim, JT Yeung & Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at [email protected]
***
We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce an infographic on ACS for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.
You can check her out on instagram at @beckysnotes01 and get her books at https://linktr.ee/Beckysnotes
=== Timestamps ===
(00:51) What is atherosclerosis?
(01:56) Modifiable & non-modifiable risk factors
(03:02) Troponins
(06:15) Layers of the heart
(08:36) What is ACS?
(11:05) Taking a history of a suspected ACS
(15:45) ACS differentials
(17:09) Investigations
(20:15) Management
(22:53) PCI vs Thrombolysis
(24:47) Long term management
(27:01) Complications
...more
31min
March 02, 2023 #12B - Pleural Effusion...in 5 minutes!
The First Principles of Pleural Effusion that can get you through your internal medicine placement: First Principles summary version.
=== Other Links ===
Check out our new website 1pm.wiki for the Notion document, free Anki flashcards, and podcast episodes.
Check out our Instagram: https://www.instagram.com/firstprinciplesofmedicine/
Recorded 28 June 2022 Co-hosts: JT Yeung, Jason D’Silva, Adian Izwan & Daniel Bontempo feat. Mo Albonajem. Produced by Rushil D'Cruz & Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at [email protected]

...more
3min
March 02, 2023 #12A - Pleural Effusion: enlightening criteria
The First Principles of Pleural Effusion that can get you through your internal medicine placement: exudative vs transudative, stony dullness, and will we ever remember Light's Criteria?
=== Other Links ===
Check out our new website 1pm.wiki for the Notion document, free Anki flashcards, and podcast episodes.
Check out our Instagram: https://www.instagram.com/firstprinciplesofmedicine/
Recorded 28 June 2022 Co-hosts: JT Yeung, Jason D’Silva, Adian Izwan & Daniel Bontempo feat. Mo Albonajem. Produced by Rushil D'Cruz & Adian Izwan.
If you have any ideas or feedback, comment on this Notion document, or shoot us an email at [email protected]
=== Timestamps ===
(01:05) What are the pleura?
(03:14) What is a pleural effusion?
(04:30) Transudative vs Exudative effusions
(09:26) Light's Criteria
(11:35) Assessing pleural effusion
(13:21) Examination signs
(16:28) (Some) Lung sounds
(18:05) Investigations
(28:21) Brief management
...more
32min

FAQs about First Principles of Medicine:

How many episodes does First Principles of Medicine have?

The podcast currently has 73 episodes available.