The First Principles of Antipsychotics that can more than get you through your psychiatry rotation: is it all about the dopamine?

=== Other Links ===

Check out our new website ⁠⁠⁠1pm.wiki⁠⁠⁠ for the ⁠⁠⁠Notion document⁠⁠⁠, free Anki flashcards, and podcast episodes.

Check out our Instagram: ⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠

Recorded 7 March 2023 Co-hosts: Broska Zeynel & Jason D'Silva feat. Renae Long & Alexander Lawrie. Produced by Adian Izwan.

If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠[email protected]⁠⁠⁠

***

We’re really excited to be collaborating with Becky from Becky’s notes, a UK based resource, to produce infographics for our visual learners out there. Becky’s notes brings together all the key topics medical students need to know in a readily available place, reviewed by specialists in the field. These visually striking notes are a refreshing change from all the boring textbooks.

You can check her out on Instagram at @beckysnotes01 and get her books at ⁠⁠⁠https://linktr.ee/Beckysnotes⁠⁠⁠

=== Timestamps ===

(01:33) The First Principles of pathways

(02:59) Dopaminergic pathways

(03:28) Mesolimbic - positive symptoms

(04:13) Mesocortical - negative symptoms

(07:17) Nigrostriatal - motor symptoms

(08:15) Tuberoinfundibular - prolactin

(09:06) Pathway summary

(10:53) Other receptors

(13:47) Antipsychotics (finally)

(14:19) Typical antipsychotics

(17:43) Negative symptoms mnemonic

(19:36) Neuroleptic malignant syndrome

(22:28) Atypical antipsychotics

(24:23) Metabolic side effects

(25:07) Summary