2º episódio, aqui vai ele.

 

Ficou um pouco maior do que queria, sobretudo porque estava sem o travão dos meus amigos Pedro e Mariana.

 

Espero que 40 minutos não seja demasiado. Caso seja, acho que o principal é dito nos 1os 20-30minutos.

 

Até amanhã.

 

Blogue esFOAMeados 

 

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GLOSSÁRIO

 

RS de ECAs

Doente crítico/urgente

·        Patient-Level Meta-Analysis of Low-Dose Hydrocortisone in Adults with Septic Shock | NEJM Evidence

 

Infecciologia, Microbiologia & Antimicrobianos

·        Evaluation of Oseltamivir Used to Prevent Hospitalization in Outpatients With Influenza | JAMA Internal Medicine

ECAs

Cardiovascular

·        Angiotensin-Neprilysin Inhibition in Mildly Reduced or Preserved EF and Worsening Heart Failure | JACC

 

·        Self-administered IN etripamil w/ symptom-prompted, repeat-dose regimen for AVN-dependent SVT - RAPID | Lancet

 

Doente crítico/urgente

·        Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults - DEVICE | NEJM

 

Endocrinologia

·       Insulina icodec

o   Once-Weekly Insulin Icodec vs Once-Daily Insulin Degludec in Insulin-Naive T2D - ONWARDS 2 | JAMA

o   Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin - ONWARDS 1 | NEJM

 

·        Incretinas

o   Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity | JAMA Network Open

o   Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial | NEJM

 

Gastroenterologia & Hepatologia

·        Randomized placebo-controlled phase 3 trial of vibrating capsule for chronic constipation | Gastroenterology

 

Geral, Geriatria & Paliativos

·        Intervention to Promote Communication About Goals of Care for Hospitalized Patients With Serious Illness | JAMA

 

Hematologia

·        Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia - PACER | NEJM

 

Infecciologia, Microbiologia & Antimicrobianos

·        Continuous vs Intermittent Meropenem Administration in Critically Ill Patients With Sepsis - MERCY | JAMA

 

Nefrologia

·        Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure - CONVINCE | NEJM

 

·        Balanced crystalloid solution versus saline in deceased donor kidney transplantation - BEST-Fluids | Lancet

 

Neurologia

·        Early versus Later Anticoagulation for Stroke with Atrial Fibrillation - ELAN | NEJM

 

·        Panax notoginseng Saponins in the Treatment of Adults With Ischemic Stroke in China | JAMA Network Open

·        Butylphthalide in Patients With Acute Ischemic Stroke - BAST | JAMA Neurology

 

Neurologia/ORL/Doente urgente

·        Semont-Plus or Epley Maneuver in Posterior Canal Benign Paroxysmal Positional Vertigo | JAMA Neurology

 

--- Normas de Orientação ---

Diagnóstico / Raciocínio Clínico e MCDs

·        Joint Advisory Statement: Emergency CT scans and IV Iodinated Contrast | RCEM-RCR

 

--- Observacionais ---

 

Revisões Sistemáticas

Doente crítico/urgente

·        Observation, aspiration, or tube-thoracostomy for primary spontaneous pneumothorax | Chest

 

Primários - Sub-análise / Coorte / Caso-controlo / Inquéritos / Análises económicas

Cardiovascular

·        P2Y12 Inhibitor Monotherapy / Dual Antiplatelet Therapy After Complex PCI | JACC

 

·        Clinical Outcomes of Intensive Inpatient Blood Pressure Management in Hospitalized Older Adults | JAMA IM

 

·        Bleeding-Related Hospitalizations During Use of Amiodarone With Apixaban or Rivaroxaban in Patients w/ AF | AIM

Diagnóstico & Raciocínio Clínico

·        Accuracy of a Generative Artificial Intelligence Model in a Complex Diagnostic Challenge | JAMA Network Open

 

·        Clinically significant contrast-associated AKI after emergent CT angiography of the cerebral arteries | EJIM

Meta-investigação & MBE

·        Lack of Treatment Efficacy Derived From Statistically Nonsignificant Results of Randomized Clinical Trials | JAMA

 

·        Prolific non-research authors in high impact scientific journals: meta-research study | Scientometrics 

 

Perspectiva

Geral

·        Update in Outpatient General Internal Medicine: Practice-Changing Evidence Published in 2022 | AJM

 

Meta-investigação & MBE

·        Detecting Selection Bias in Observational Studies—When Interventions Work Too Fast | JAMA Internal Medicine

 

·        Promoting Ethical Integrity in Authorship Attribution: Who Can Help More? | Acta Médica Portuguesa

 

·        Catalogue of bias: novelty bias | BMJ-EBM