The paper introduces SGS (single-cell and spatial genomics system), a new, open-access genome browser designed to empower the integrative and collaborative exploration of complex single-cell and spatial multimodal data. Developed to overcome the visualization challenges posed by high-dimensional omics data, SGS offers a user-friendly graphical interface (GUI) that requires no programming expertise. Key features include two main modes—SC (single-cell) and SG (spatial genomics)—which enable synchronized, multi-panel visualization for diverse data types like transcriptomics and epigenomics. Furthermore, SGS supports 3D spatially resolved transcriptomics (SRT) data visualization and advanced comparative analysis features like scCompare and dual-chromosome mode to help researchers extract novel biological insights.

References:

• Xia T, Sun J, Luo Y, et al. Empowering integrative and collaborative exploration of single-cell and spatial multimodal data with SGS genome browser[J]. Cell Genomics, 2025, 5(5).