#276 Understanding the chemistry of NVG-291’s efficacy for Rewiring SCI Recovery with Inventor Dr. Brad Lang

Brad Lang, PhD, is the neuroscientist and biotech inventor of the ISP drug, the basis of the NVG-291 trials which recently showed efficacy. His work has helped pave the way for one of the most promising new treatments for spinal cord injury in decades. Brad shares the story of how his early research led to the discovery of the intracellular sigma peptide (ISP), a molecule with the potential to unlock axon regeneration and repair damaged neural pathways. We explore the science behind ISP, the challenges of moving from lab discovery to human trials, and the role of persistence at big ideas (a mission imprinted on him by the late Dr. Jerry Silver) when the odds—and the nervous system—seem stacked against recovery.  Along the way, Brad reflects on the emotional journey of being a scientist chasing a breakthrough, the worldwide attention on NervGen’s NVG-291, and the hope these advances bring not only to the SCI community but to the future of treatments for conditions once thought untreatable, and the potential reshaping of lives for those living years with SCI.

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A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel.  Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

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