The Vitality Formula

#28: GLP-1 Side Effects Explained: What’s Normal and What Helps


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GLP-1 medications like Ozempic, Wegovy, and Zepbound can improve weight loss and blood sugar regulation, but they also come with side effects. In this episode of The Vitality Formula, physician Dr. Marie Livesey explains the most common GLP-1 side effects and what actually helps.

You’ll learn why symptoms like nausea, constipation, fatigue, reflux, hair shedding, and muscle loss can occur when starting these medications and what is happening physiologically inside the body. Dr. Livesey also shares practical strategies that can make GLP-1 treatment more manageable while supporting long-term metabolic health.

GLP-1 medications influence appetite signaling, gastric emptying, and blood sugar regulation, which means many of the side effects people experience are predictable physiological responses rather than random complications. Understanding these mechanisms can help patients navigate treatment with more confidence.

What You’ll Learn

• Why nausea is the most common GLP-1 side effect
• Why constipation occurs and how to improve gut motility
• Why some patients experience fatigue when starting GLP-1 medications
• How slower gastric emptying can contribute to reflux symptoms
• Why hair shedding sometimes occurs during weight loss
• How to protect muscle mass while losing weight on GLP-1 medications

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If you want a physician-led framework to help you think clearly about weight loss, hormone care, and modern health advice, you can download The Metabolic Clarity Guide .

Connect with Dr. Marie today!
Instagram: @dr.mlivesey
LinkedIn: www.linkedin.com/in/drmlivesey
Website: https://www.livelyholistichealth.com

This podcast is for informational purposes only and does not constitute medical advice or establish a provider–patient relationship.

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The Vitality FormulaBy Dr. Marie Livesey