Charles V, Holy Roman Emperor also known as Carlos was born in 1500 and he lived for 58 years, dying in the Spanish monastery of Yuste of malaria. As we list his titles, King of Spain, King of the Netherlands, Flanders and Belgium, Emperor of Austria and Hungary, ruler of much of Italy including Milan, Sicily, Sardinia and Naples and Emperor of the Americas, the listener is apt to think that his realm encompassed much of the known world, as indeed it did, but this does not take account of the periphery.