Paper Talk

433-Closed-Loop Wearable Neurostimulation System


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This research presents a wearable, closed-loop system designed to treat hemifacial spasms (HFS) through a combination of high-precision sensing and targeted nerve stimulation. Integrated into a discreet eyewear platform, the device utilizes self-powered triboelectric sensors enhanced by specialized nanomaterials to detect minute, involuntary facial muscle contractions in real time. When the system identifies a spasm, it automatically triggers a customized electrical stimulator to deliver neuromodulation that inhibits abnormal neural activity. Clinical validation involving patients demonstrated that this technology achieves a 98% recognition accuracy and effectively improves facial symmetry by reducing the severity of contractions. By offering a non-invasive and portable alternative to risky surgeries or temporary injections, this integrated platform significantly enhances patient compliance and quality of life. The system also shows promise for broader applications in health monitoring, such as tracking heart rate variations through arterial pulse sensing.

References:

  • Qu X, Wan J, Zhao H, et al. Closed-loop wearable neurostimulation system with triboelectric sensing to alleviate hemifacial spasms[J]. Nature Communications, 2025, 16(1): 11148.
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Paper TalkBy 淼淼Elva