The 49ers lost in another blowout, 35-10, to the Bills on Sunday night, cementing themselves as unserious players for the rest of the season in the NFC. The Niner Noise Podcast is here to discuss the matchup (sort of) but also get into what the loss of Christian McCaffrey and Jordan Mason means for the rest of this year and how the Niners can take advantage of the rest of the season.

The Niner Noise Podcast on the 49ers, the FanSided Podcast Networks' San Francisco 49ers pod, is your source for 49ers news, in-depth analysis, exclusive interviews, and more!

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