How can regulators assess the risks and mitigate them sensibly without stifling the enormous potential benefits that Fourth Industrial Revolution technologies have to offer? In episode 5 of ‘Shaping the Fourth Industrial Revolution’, we examine some of the emerging tools regulators are developing to blunt the horns of this particular dilemma. We are joined by Karen Yeung, Director of the Centre for Technology, Ethics, Law and Society at King’s College London; Nita Farahany, Professor of Law and Philosophy at Duke University; Dave Guston, Co-director of the Consortium for Science, Policy and Outcomes at Arizona State University; Wendell Wallach, Chair of Technology and Ethics Studies at the Interdisciplinary Center for Bioethics, Yale University; Gillian Hadfield, legal scholar and author of ‘Rules for a Flat World’; Rob Sparrow, ethicist and Professor at Monash University in Melbourne; Sheila Jasanoff, Pforzheimer Professor of Science and Technology Studies at the Harvard Kennedy School; and Professor Kyong-Su Yi, Head of the Vehicle Dynamics and Control Lab at Seoul National University.