Researchers introduced scRank, a computational tool using single-cell transcriptomics and gene regulatory networks to identify drug-targeted cell types. They identified Ex_9 neurons as targets for SSRIs in MDD and found that Tanshinone IIA binds CTSB in macrophages.
References:
* scRank infers drug-responsive cell types from untreated scRNA-seq data using a target-perturbed gene regulatory network...去小宇宙查看完整单集简介
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