Drug Cards Daily

#55: digoxin (Digox) | An Antiarrhythmic Agent for HFrEF, AFib, and PSVT conversion


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Digoxin also goes by the brand names Digox, Digitalis, and Lanoxicaps. Digoxin comes as tablets, a solution, and an injection. In both Adults and Pediatrics, when calculating doses it is important to use the patient’s lean body weight (LBW) with dose adjustments based on levels. It is important to also remember that concentrations of >2 ng/mL lead to digoxin toxicity and can also be identified with signs and symptoms such as anorexia, nausea, vomiting, and visual changes. The most common indications are for treating Heart Failure with reduced Ejection Fraction (HFrEF) and Atrial Fibrillation (AFib). Digoxin is poorly protein bound with a long duration of action between 3-4 days. THe most common side effects are dizziness, headache, bradycardia, weakness, and confusion. 

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