This research explores a novel CAR-T cell therapy designed to treat solid tumors by targeting the tumor microenvironment rather than cancer cells directly. Scientists engineered armored CAR-T cells to deplete immunosuppressive macrophages—specifically those expressing FOLR2 or TREM2—while simultaneously delivering the potent immune stimulant IL-12. In animal models of ovarian, pancreatic, and lung...去小宇宙查看完整单集简介
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