In this episode, Andy Walsh sits with Dr. Denise Bronner, a scientist-turned-strategist who has spent 15 years bridging the gap between the lab bench and the boardroom. As the founder of Empactful Ventures, Denise deconstructs the high-stakes reality of due diligence, transforming it from a “pop quiz” into a strategic mirror for operational maturity.

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The Conversation

Andy and Denise dive into the “hard edge” where complex science meets venture capital. They discuss why founders must stop hiding from their data and start using it to build a narrative that survives the scrutiny of Seed through Series A rounds. From the “Pac-Man effect” of 2026 market consolidation to the emotional toll of M&A “lock-ins,” this is a raw look at what happens when the lights come on in the data room.

Chapters

• 00:00 Lab to Leadership: The Scientist’s Journey
• 02:43 Bridging Science and Business
• 08:23 Data Storytelling: Science Meets Strategy
• 14:21 Understanding Your Investor Audience
• 17:10 The Reality of Due Diligence
• 22:48 Mergers & Acquisitions: Survival of the Transparent
• 28:23 The Founder’s Toll: Empathy in the Exit
• 40:10 The Pac-Man Effect: 2026 Market Trends

“Due diligence isn’t a pop quiz—it’s a mirror. If you organize your truth, pressure helps you; it doesn’t hurt you.” — Denise N. Bronner, Ph.D.

Who Should Listen:

Founders in regulated spaces (Healthtech/Biotech), Ops leads tasked with data rooms, and investors refining their DD checklists.

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Music Credit

“Neptuno” – Phondupe (Album: Onykia)