This research explores how cells terminate the integrated stress response (ISR) to resume normal protein synthesis. The study identifies that the protein R15B plays a critical role by facilitating the dephosphorylation of P-eIF2 while it is still attached to the translation factor eIF2B. Previously, it was unclear how this process occurred because the inhibited complex appeared structurally inacce...去小宇宙查看完整单集简介
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