This research study identifies sildenafil as a potential treatment for Leigh syndrome, a currently untreatable and severe mitochondrial disorder. By screening thousands of existing drugs on patient-derived stem cells, scientists discovered that this PDE5 inhibitor can correct cellular defects, such as abnormal mitochondrial membrane potential and impaired calcium regulation. The drug demonstrated ...去小宇宙查看完整单集简介
前往小宇宙评论区与主播互动